New in 2016- *****No Submission Fees***

AJP-Lung no longer charges submission fees. Send us your best work, today!

Respiration Section Banquet At EB2016 - ***DEADLINE EXTENDED 2/15/16***

Dear Respiration Section Members,

The website for purchasing tickets for the Respiration Section Banquet  at Experimental Biology in San Diego is now live (see below)! The dinner will take place on  Monday,  April 4 starting at 6:30 pm at Maritime Museum. Tickets to the Respiration Section Banquet  is quite popular and sells out very quickly.

***DEADLINE HAS BEEN EXTENDED TO 2/15/16*** Don’t hesitate! Buy your tickets today!

Thanks to those  who have already purchased tickets.  For USA Residents, your tickets will be mailed out around the first week of March.  For International Ticket Holders, you will pick up your tickets onsite.  An email will be sent to you around the first week of March with details on where to pick up your tickets at EB16.

Please click on the link below to purchase your tickets today.

Respiration Section Banquet



Best regards,

Ann Marie Bocus
Sections Coordinator

AJP-Lung Submissions Rise

We would like to thank all of our contributors in 2015. Our submissions  have increased over 20% from 2014.   We were, in fact, one of the few APS journals to show growth.

Thank you for your submissions.

The journal title is			AJP-Lung
Published research pages to date are			2361
Published editorial pages to date are			407
Projected total pages for 2015 are			2768
The page cap is			2400
Pages (over)/under cap are			(368)
	# Research Manuscripts recv thru 4Q 2015	# Research Manuscripts recv thru 4Q 2014	YTD Change No.	YTD Change %
AJP-Cell	319	374	-55	-15%
AJP-Endo	525	613	-88	-14%
AJP-GI&L	419	436	-17	-4%
AJP-Heart	852	833	19	2%
AJP-Regu	496	480	16	3%
AJP-Renal	462	518	-56	-11%
AJP-Lung	426	356	70	20%
Total AJP	3,499	3,610	-111	-3%

New insights into the complex role of estrogen in influenza

In the recent 2009 H1N1 pandemic young adult women experienced greater mortality than age-matched men. Murine models show worse outcomes in adult females compared to males. So estrogen is bad for influenza, right? Not so fast! In a recent AJP Lung paper that has garnered media attention (http://www.sciencedaily.com/releases/2016/01/160112093424.htm),  Dr. Sabra Klein and colleagues report that estrogen or compounds with estrogen-like activity actually reduce influenza virus replication in primary human nasal epithelial cells—but only in those from female, not male, donors. The effect is mediated through the 2nd genomic estrogen receptor, ER-beta, since neither of the other two ER receptors (ER-alpha or GPR30) were expressed in the nasal epithelial cells, and an ER antagonist could block estrogen’s effects. Transcriptome profiling showed marked down-regulation of zinc-finger proteins, an intriguing clue to possible molecular mechanisms for both the anti-proliferative effect and the sex selectivity . This work expands on past studies from the Klein lab showing that pharmacologic or high levels of estrogen can have beneficial effects on influenza outcome in mouse models, while recognizing that normal low levels may have paradoxical pro-inflammatory or harmful effects. The biphasic nature of hormone effects is well known, and these data are a fascinating addition to the important role of sex hormones in modulating outcomes in infectious disease.

To find out more about this interesting study, please check out the full text of this article. It is available for free on the AJP-Lung website, even for those with no subscription to APS journals:
http://ajplung.physiology.org/content/early/2015/12/17/ajplung.00398.2015

Dr. Lester Kobzik

A few thoughts on reviewers´ conflict of interest

Over the past decade, it has become customary for most peer-review journals (including APS journals) to ask potential reviewers to declare potential conflict of interests. Circumstances that may be perceived as conflict of interest typically include e.g. a close personal or professional relationship between the reviewer and any of the authors, or mutual involvement in a contentious dispute on the topic of the manuscript. However, on a much broader scale, we all (as reviewers and editors) have conflicts of interest, which relate to an ever more precious and scarcer resource: time. When reviewing manuscripts, we extract time from our busy schedules for a task that – by its anonymous nature – constitutes primarily a quiet service to our community by which we pay back what we ourselves receive when our own manuscripts are reviewed by expert reviewers providing – hopefully – meaningful and constructive advice and guidance. Such good citizenship typically yields little-to-no immediate merit for the reviewers themselves. Some reviewers, however, tend to strive for some indirect revenue, by suggesting to authors to reference specific papers which – of course by pure coincidence - happen to be their own. In some instances, this will be entirely justified, as the authors may have missed to take an important piece of literature into consideration which just happens to be authored by the reviewer. In other instances, however, such recommendations will be less motivated by our surge for scientific accuracy but rather by our vanity. Such hijacking of what is essentially a pro bono service for self-promotion constitutes a significant and unacceptable conflict of interest. No-one should be coerced to cite "paper xyz“, unless it serves the purpose to improve the scientific valor and accuracy of a manuscript. Authors submitting manuscripts to AJP-Lung should know that the editorial board and our reviewers work hard to ensure constructive and unbiased reviews of all manuscripts in a fair and timely manner that are based on scientific merit alone. In 2014, the average time to first decision for submitted manuscripts was 22.3 days.

Wolfgang Kuebler, Associate Editor

AJP-Lung will offer CME credit in 2016

The American Physiological Society (APS) is pleased to announce that beginning January 2016 it will offer a manuscript review Continuing Medical Education (CME) activity to the reviewers of the American Journal of Physiology – Lung Cellular and Molecular Physiology (AJP‐Lung) as a benefit of reviewing for the journal. The APS is pleased to be working in collaboration with Washington University School of Medicine, which is administering this CME activity. Washington University School of Medicine is a CME provider accredited by the Accreditation Council for Continuing Medical Education (ACCME) and designates the AMA PRA Category 1 CreditsTM within the American Medical Association Physician Recognition Award (AMA PRA) system.

A participating reviewer may be awarded 3 AMA PRA Category 1 CreditTM per review; a reviewer may claim up to 15 AMA PRA Category 1 CreditTM per year.

Our Associate Editors will be responsible for assigning a score to each review. This score will serve as the measure of acceptability of the review for CME credit. The scoring parameters to receive CME credit are a maximum 14‐day turnaround with a score of "Good" or higher.

Reviewers who indicate an interest in earning CME for their review will receive written notification about whether they earned CME credit based on the quality of the review. This notification will serve as documentation of their earned CME credit. Please note that 1) the CME credit will only be given for first reviews of manuscripts; reviewers will not receive additional credit for revised versions 2) there will be no cost to the reviewer for receiving CME credit as the program is supported by the APS and 3) credit will be awarded annually.

APS Select December 2015

AJP-Lung would also like to recognize one of our papers who was honored with the APSselect selection for December 2015. "DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease" was written by Jodie Birch and her colleagues. Please click on the link below to access this important article.

http://ajplung.physiology.org/content/309/10/L1124